Dr. Grant obtained his B.Sc. in Biochemistry (1979) from McMaster University and his Ph.D. (1986) in Pharmacology at the University of Toronto, where he worked under the mentorship of the late Werner Kalow, the internationally recognized 'father of pharmacogenetics'. He then joined the laboratory of Professor Urs Meyer in the Department of Pharmacology at the Biozentrum of the University of Basel, Switzerland, to investigate the biochemical and molecular mechanisms of common polymorphisms of human drug-metabolizing enzymes. In 1989 Dr. Grant joined the Research Institute of the Hospital for Sick Children in Toronto as a Scientist and then as a Senior Scientist, with academic appointments to the Departments of Pediatrics and Pharmacology and the Leslie Dan Faculty of Pharmacy at the University of Toronto. Following a two-year leave to assume a management position in industry as Senior Director of Pharmacogenetics at Orchid Biosciences in Princeton, New Jersey, he returned to Toronto in 2002 to take up his current position as Professor and Chair of the Department of Pharmacology and Toxicology in the Faculty of Medicine, as well as a Professor in the Leslie Dan Faculty of Pharmacy at the University of Toronto.

Dr. Grant's past and present research interests focus on the use of human population-based screening approaches as well as biochemical, cellular, molecular, genetic and gene-targeted animal model systems to study the causes and consequences of interindividual variations in drug response and chemical toxicity that result from genetically variable enzymes of drug metabolism. His work has been supported by funding from the Canadian Institutes of Health Research, The National Cancer Institute of Canada and the Cancer Research Society.